Bjarki Johannesson

Bjarki Johannesson

Company: The New York Stem Cell Foundation

Job title: Senior Investigator


High-Throughput Generation of Standardized Human iPSC Derived Pancreatic Beta Cell Islets 9:15 am

• We have established an automated pipeline for the optimization of iPSC-based differentiation protocols • This pipeline is currently being applied to the differentiation of pancreatic beta cell islets from human iPSC • Automation of beta islet differentiation allows parallel differentiation of multiple patient derived cells for population-based disease modeling and drug screening • Protocol…Read more

day: Day Two

Panel Discussion: Exploring Gene Editing as a Means to Protect Transplanted Cells from a Patients’ Immune System 4:15 pm

• Learning how the advent of novel gene editing tools provides unique opportunities to disassemble MHC components in stem cell lines used to produce pancreatic-lineage cells to prevent presentation of alloantigens and autoantigens by the stem cell-derived beta cells and recognition by memory autoimmune cells in T1D patients • To what extent can eliminating MHC…Read more

day: Day One

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